Troubleshooting community setups: see the compatibility result using temperature, pH, GH/KH, adult size, behavior, schooling needs, and predator/prey rules.
Short answer: Sometimes, but only if the warnings are handled. Plan for at least 20 gallons before adjusting for group size, filtration, and aquascape layout.
Data confidence: high
Verified sources: GloFish care guidance | SeriouslyFish Danio rerio
glofish danio | cherry shrimp | glofish danio | cherry shrimp
This verdict assumes normal social groups, not one stressed specimen. GloFish Danio should be planned at 6+; Cherry Shrimp should be planned at 10+ before judging long-term compatibility.
For shrimp-heavy tanks, check adult shrimp and shrimplet risk separately. A fish may ignore adult shrimp but still hunt babies, molting shrimp, or stressed individuals.
A compatibility score checks adult size, temperature, pH, hardness, temperament, and tank volume. Real tanks add variables the score cannot see directly: feeding aggression, cave ownership, plant cover, and whether fish can constantly see each other.
GloFish Danio and Cherry Shrimp use different swim zones, but feeding time and open sightlines can still change behavior. Start with at least 20 gallons, then use hardscape, tall plants, and separated feeding zones to reduce chasing before it becomes a pattern.
Observed photo context
These photos show observed aquarium setups for the selected species. They are useful context, but they do not change the compatibility result or replace tank-size, temperament, group-size, and water-parameter checks.
Confidence: high. Aggression, predator/prey, shrimp risk, schooling, and tank size rules are evaluated from curated freshwater attributes.
Problems can happen even when the gallon number is technically adequate. Check feeding order, repeated access to the same cave or plant mass, school size, and whether the aquascape gives either fish a direct line of sight across the whole tank.
Use tall plants, rock piles, driftwood, and separate feeding stations so a dominant fish cannot patrol one open lane from end to end.